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Polynucleotides

Polynucleotides for anti-ageing and skin rejuvenation

Ideal for those wishing to treat the signs of ageing, or those wishing to treat dull and fragile skin

Polynucleotides are an injectable skin booster, primarily derived from salmon DNA, making them natural, biocompatible, and biodegradable. They are predominantly used to reduce wrinkles, stimulate cellular regeneration, collagen synthesis, and tissue repair.

These skin-boosting and regenerative injectables have become a popular choice for patients looking to combat the signs of ageing and address common skin concerns.

We offer Polynucleotides at both our Reading (Queens Road) and London (Harley St) locations.

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Pricing: From £578 | Book A Consultation

 

Key Benefits of Polynucleotides

Polynucleotides are the next generation of powerful anti-ageing solutions, scientifically proven to regenerate the skin. Natural, compatible and biodegradable, Polynucleotides are scientifically proven to:

  • Visibly lift and tighten the skin
  • Stimulate collagen and elastin production
  • Repair and regenerate tissue
  • Repair skin at a cellular level
  • Hydrate and retain moisture
  • Reduce fine lines and wrinkles
  • Improve skin texture and tone
  • Reduce inflammation and redness
  • Long-lasting results

 

Frequently asked questions about Polynucleotides

Polynucleotides are primarily derived from salmon DNA, making them natural, biocompatible, and biodegradable. According to international Facial Aesthetics Trainer, Dr. Bob Khanna, polynucleotides act as "food or medicine for cells," promoting collagen and elastin production while enhancing the skin’s extracellular matrix (that's the vital structural layer that keeps skin youthful and firm!).

While different manufacturers might refer to polynucleotide treatments as biostimulators, biofillers, or biorevitalisers, they all revolve around this powerful anti-ageing ingredient.

Traditional anti-wrinkle treatments (like Botox) typically last 3-4 months. Polynucleotide treatments, on the other hand, can last between 6-12 months, with ongoing improvements to skin quality long after the initial effects.

Unlike dermal fillers that simply plump the skin temporarily, polynucleotides regenerate skin at the cellular level. They boost hydration, collagen production, and skin elasticity. Some treatments that we offer, such as Pluryal Densify, combine polynucleotides with hyaluronic acid for added volume.

While most anti-ageing treatments take months to show improvements, you can see visible results from polynucleotide treatments within approximately 3 weeks, with full effects becoming more apparent over several months. The skin will gradually improve in texture, firmness and hydration.

When combined with hyaluronic acid, the effects can be immediate!

Usually 2-3 treatments, 4 weeks apart are required to achieve optimal results. A top up every 12 months is recommended to continue to enjoy the effects.

At DrBK, we offer optional numbing cream before the treatment for those that are sensitive to needles. However most patients, particularly those who are used to 'botox', fillers or microneedling, may feel they do not require numbing at all.

We offer polynucleotide treatments at both of our locations in Reading (Queens Road) and London (Harley St). Book now.

At DrBK Reading and Harley St, we offer a range of polynucleotide treatments tailored to different skin and hair concerns. Here are the key options:

1) Pluryal® Silk

One of the most popular polynucleotide treatments at DrBK Reading & Harley St is our Pluryal Silk. This is a skin densifier with polynucleotides, designed for delicate areas like under the eyes (to reduce dark circles), around the mouth, hands, chest, and even postpartum stretch marks on the abdomen. Perfect for those seeking to target early signs of ageing in sensitive areas.

2) Pluryal® Densify

This repair treatment combines polynucleotides, hyaluronic acid, and mannitol (an antioxidant) to restore lost volume and improve skin texture. Ideal for rejuvenating dull, damaged skin, or fatigued areas of the face—except for the under-eye region.

3) Pluryal® Hair Density

Our latest solution for hair loss, Pluryal Hair Density nourishes the scalp and promotes hair regrowth. It’s effective for thinning hair, androgenic alopecia, post-transplant recovery, and temporary hair loss conditions like telogen effluvium.

 

Before and After Polynucleotide Treatment

 

Other injectable skin solutions at DrBK

As well as new Polynucleotides, we do offer other injectable skin solutions, and they are often combined for optimal results. To find out which solution(s) is best for your desired goals, please book a consultation with our friendly team.

PRP is often used in conjunction with polynucleotides for optimal results.

PRP (platelet-rich-plasma) treatment involves using a patient's own blood to promote cellular healing. It involves collecting a small amount of blood from your arm (similar to a routine blood test) which is then placed in a centrifuge which separates platelets from other blood cells. The plasma-rich-platelets are then injected into the affected area. PRP contains growth factors to help our bodies heal and regenerate.

Using the Pluryal Mesoline Range; Specifically developed products that work to target a variety of skin complaints.

Following topical application, the products are fed deeper into the skin using a mesoline roller (otherwise known as microneedling), which introduces microscopic holes in the skin to allow the quantities of volume, hydration, vitamins and minerals into the skin (or scalp) to help it rejuvenate and repair itself.

Products include;

  • Antiox: Antioxidant action for damaged and dull skin. Fights premature ageing.
  • Clear: Designed to regulate skin sebum, reduce acne and other skin imperfections. Also reduces inflammation of the skin.
  • Shine: Enriched with Vitamin C to reduce blemishes and reduce brown spots/pigmentation.
  • Tight: Lifting action to tighten skin and reduce dilated pores.
  • Refresh: Revitalising action to target dullness and lack of elasticity.
  • Radiance: Brightening action to reduce dark circles/pigmentation.

 

Not sure what treatment option is best for you?

If you are unsure which treatment option would be best for you, please book a consultation at either our Reading or London locations and we will be able to advise you on the best course of action for your needs and desires. All full face consultations in Reading include an in-depth analysis using the VISIA Skin Analysis device.

 

Testimonials

"I spent years not being able to smile as I hated my teeth, I was told many years ago that it would be impossible to straighten them, this left me with no confidence. Then I was told to visit Dr Bob Khanna. Today I feel great about myself, I have learned to smile again & I owe this to Dr Bob & his wonderful team. Many many thanks Dr Khanna for the work you have done, I will remain a loyal customer to you in the future." - Annie

"I could not be happier with the results Prof Bob Khanna has given me, from the very start the staff at Dr BK clinic were very informative and helpful. My nose now looks as it did before I damaged it, Prof Bob Khanna listened to my exact needs and as to what I wanted to achieve, and this shows in the way my nose now looks, I will definitely continue to come back to the clinic for future treatment." - Jason

"If you want a comprehensive, safe, quick and satisfactory treatment for your face just visit dr bob Khanna. I got my tear troughs, cheeks & non-surgical facelift done yesterday, it was pain free, took less than 20 minutes, huge transformation in a very natural way immediately and now I can't be happier. Would never get safer hands than Dr Bob's. He is a magician, love you for making me love my mirror again" - Rand

"I had been diagnosed with bruxism by my dentist and had been wearing a plastic mouthpiece every night for over five years. I read about the BK Clinic in a national newspaper and made an appointment. The team were very warm, friendly and put me at ease. Professor Khanna diagnosed my problem within minutes. Within 2 weeks I was pain-free, sleeping better and my ugly mouthpiece was ditched. I would not hesitate in recommending the DrBK Clinic, Professor Khanna is extremely knowledgeable and passionate about what he does and I only wish I had discovered his services sooner." - Sarah

"Your laser hair removal is the best treatment ever, it has been so effective and I never have to worry again about waxing, I was so grateful to find it was also not painful compared to other laser treatments I have had in the past. It felt like a warm massage. Thank you." - Cassie

Professor Bob And his wonderful caring team is the only clinic to go. I am always reassured and always feel welcome. I feel I am in the magic hands of Professor Bob. Pain free fabulous results. He simply loves his profession loves people and cares. What more an you ask for. Professor Bob achieves his work of art." - Renee

"I couldn't fault my experience, Prof Bob Khanna and the staff at the clinic were friendly and professional at all times. I would recommend visiting the clinic as you will be in the best hands. 10/10 for service and results." - Natasha

"Fantastic place, well looked after from the moment you walk through the door. I could not be any happier with my results there are amazing, wouldn't recommend anywhere else." - Jemma

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