
Polynucleotide Treatments
Polynucleotides for anti-ageing and skin rejuvenation
Polynucleotides – The next generation of powerful biostimulators, scientifically proven to regenerate the skin from within
What are polynucleotides?
Polynucleotides are an injectable skin booster, primarily derived from salmon DNA, making them natural, biocompatible, and biodegradable. They are predominantly used to reduce wrinkles, stimulate cellular regeneration, collagen synthesis, and tissue repair.
These skin-boosting and regenerative injectables have become a popular choice for patients looking to combat the signs of ageing and/or address common skin concerns.
_______________________________
Pricing: From £578 per session
How do polynucleotides work?
Polynucleotides are a component predominantly derived from salmon DNA, making them natural, compatible and biodegradable. Dr Bob Khanna explains that polynucleotides are “like food or medicine for cells, making them produce collagen and elastin and helping to improve the extracellular matrix” (that’s the structural support layer within our skin that keeps us looking youthful, containing those fibrous elements such as collagen, elastic etc).
Sometimes, Polynucleotides treatments can be referred to as Biostimulators, Biofillers, or Biorevitalisers (depending on the manufacturer and composition), but they all contain the core anti-ageing ingredient; polynucleotides.
Polynucleotides are scientifically proven to:
- Stimulate and boost collagen and elastin production
- Durably and efficiently repair the skin (and hair) at a cellular level
- Hydrate the skin at a cellular level
- Improve tissue firmness and elasticity
- Have anti-inflammatory properties
- Promote cellular renewal
Which means they are ideal for:
- Lifting and tightening the skin
- Improving skin texture and smoothness
- Brightening the skin
- Increasing volume within the skin
- Minimising acne scars
- Minimising stretch marks
- Minimising/restoring hair loss
Dr Bob Khanna’s NuFace Protocols
Dr Khanna’s unique combination of Polynucleotides and Biofillers, for the face, neck and hands
Dr Bob Khanna’s NuFace protocol has become a popular treatment amongst our patients, incorporating both biofillers and polynucleotides into the same treatment, for the ultimate youthful glow.
Dr Bob’s NuFace protocols are unique to the DrBK Clinic, and are ideal for cases that require both volume restoration and skin rejuvenation/tightening at a cellular level.
_______________________________
Pricing
NuFace | NuNeck | NuHands
- Per area: £650 – £995
NuFace Full
- 4 areas: £2950
- 8 areas: £4950
Polynucleotides treatment before and after
Polynucleotide treatment FAQs
What are polynucleotides made out of?
Traditional anti-wrinkle treatments (like Botox) typically last 3-4 months. Polynucleotide treatments, on the other hand, can last between 6-12 months, with ongoing improvements to skin quality long after the initial effects.
How much is polynucleotide treatment?
Polynucleotide treatment sessions with us start at £578. For NuFace, areas range from £650 - £950 or we offer full packages, with 4 areas at £2950 and 8 areas at £4950.
How long do polynucleotides take to work?
While most anti-ageing treatments take months to show improvements, you can see visible results from polynucleotide treatments within approximately 3 weeks, with full effects becoming more apparent over several months. The skin will gradually improve in texture, firmness and hydration.
When combined with hyaluronic acid (such as in our NuFace Protocol), the effects can be immediate!
How many sessions of polynucleotides do you need?
Usually 3 treatments, 4 weeks apart are required to achieve optimal results. A top up every 12 months is recommended to continue to enjoy the effects.
Are polynucleotides safe?
Yes, polynucleotides are considered very safe for facial aesthetic treatments. They are biocompatible molecules naturally found in the body and are carefully purified for cosmetic use. Clinical studies have shown they are well-tolerated, with minimal risk of allergic reactions or side effects. As with any injectable treatment, it’s important to have them administered by a qualified professional to ensure the highest safety standards.
What's the difference between polynucleotides and dermal fillers?
Unlike dermal fillers that simply plump the skin temporarily, polynucleotides regenerate skin at the cellular level. They boost hydration, collagen production, and skin elasticity.
Dr Khanna's NuFace Protocol combines polynucleotides with biofillers (an advanced dermal filler designed for improving skin quality alongside volume restoration).
What's the difference between polynucleotides and your other biostimulators?
While both treatments fall under the category of biostimulators, their ingredients, mechanisms, and use cases are significantly different.
- Polynucleotides are new generation cellular repair stimulators, ideal for deeper concerns and sensitive areas.
- Mesotherapy Biostimulators are vitamin-rich skin boosters, perfect for hydration, prevention, and surface-level radiance.
Each offers a unique therapeutic approach, and the choice between them depends on your individual skin condition, age, and treatment goals. In many cases, they can be combined in a personalised protocol for enhanced results. The best option for you will be discussed with your practitioner.
What's the difference between other polynucleotide treatments and Dr Khanna's NuFace Protocol?
Prof Khanna’s unique NuFace Protocol incorporates both biofillers and polynucleotides into the same treatment. It offers unparalleled results, both to replace volume loss and provide exceptional skin rejuvenation. The NuFace Protocol is ideal for the more severe cases of volume loss.
What are biofillers?
We use the latest biofillers from Pluryal®. Regular fillers are typically used to restore the volumes of the skin by filling its depressions; Biofillers, on the other hand, act way beyond regular fillers. Whilst they increase volume similar to normal dermal fillers, Biofillers also act as biostimulators, carefully healing the skin and boosting the production of new cell layers, ensuring maximum hydration at every cellular level and increasing skin’s smoothness, elasticity, and firmness.
More-natural looking results and migration prevention
Pluryal® Biofillers are manufactured using using 3 different types of hyaluronic acid, whose particles are much smaller than those used in standard products. This promotes the penetration and distribution of the dermal filler in the tissues, preventing migration and promoting more natural-looking results.
Do Polynucleotide treatments hurt?
At DrBK, we offer optional numbing cream before the treatment for those that are sensitive to needles. However most patients, particularly those who are used to 'botox', fillers or microneedling, may feel they do not require numbing at all.
Which DrBK clinic offers Polynucleotide treatments?
We offer polynucleotide and NuFace treatments at both of our locations in Reading (Queens Road) and London (Harley St). Book now.