Polynucleotide Treatments

Polynucleotides for anti-ageing and skin rejuvenation

Polynucleotides – The next generation of powerful biostimulators, scientifically proven to regenerate the skin from within

What are polynucleotides?

Polynucleotides are an injectable skin booster, primarily derived from salmon DNA, making them natural, biocompatible, and biodegradable. They are predominantly used to reduce wrinkles, stimulate cellular regeneration, collagen synthesis, and tissue repair.

These skin-boosting and regenerative injectables have become a popular choice for patients looking to combat the signs of ageing and/or address common skin concerns.

_______________________________

Pricing: From £578 per session

 

How do polynucleotides work?

Polynucleotides are a component predominantly derived from salmon DNA, making them natural, compatible and biodegradable. Dr Bob Khanna explains that polynucleotides are “like food or medicine for cells, making them produce collagen and elastin and helping to improve the extracellular matrix” (that’s the structural support layer within our skin that keeps us looking youthful, containing those fibrous elements such as collagen, elastic etc).

Sometimes, Polynucleotides treatments can be referred to as Biostimulators, Biofillers, or Biorevitalisers (depending on the manufacturer and composition), but they all contain the core anti-ageing ingredient; polynucleotides.

Polynucleotides are scientifically proven to:

  • Stimulate and boost collagen and elastin production
  • Durably and efficiently repair the skin (and hair) at a cellular level
  • Hydrate the skin at a cellular level
  • Improve tissue firmness and elasticity
  • Have anti-inflammatory properties
  • Promote cellular renewal

Which means they are ideal for:

  • Lifting and tightening the skin
  • Improving skin texture and smoothness
  • Brightening the skin
  • Increasing volume within the skin
  • Minimising acne scars
  • Minimising stretch marks
  • Minimising/restoring hair loss

Dr Bob Khanna’s NuFace Protocols

Dr Khanna’s unique combination of Polynucleotides and Biofillers, for the face, neck and hands

Dr Bob Khanna’s NuFace protocol has become a popular treatment amongst our patients, incorporating both biofillers and polynucleotides into the same treatment, for the ultimate youthful glow.

Dr Bob’s NuFace protocols are unique to the DrBK Clinic, and are ideal for cases that require both volume restoration and skin rejuvenation/tightening at a cellular level.

_______________________________

Pricing

NuFace | NuNeck | NuHands

  • Per area: £650 – £995

NuFace Full

  • 4 areas: £2950
  • 8 areas: £4950

 

Polynucleotides treatment before and after

 

Polynucleotide treatment FAQs

Traditional anti-wrinkle treatments (like Botox) typically last 3-4 months. Polynucleotide treatments, on the other hand, can last between 6-12 months, with ongoing improvements to skin quality long after the initial effects.

Polynucleotide treatment sessions with us start at £578. For NuFace, areas range from £650 - £950 or we offer full packages, with 4 areas at £2950 and 8 areas at £4950.

While most anti-ageing treatments take months to show improvements, you can see visible results from polynucleotide treatments within approximately 3 weeks, with full effects becoming more apparent over several months. The skin will gradually improve in texture, firmness and hydration.

When combined with hyaluronic acid (such as in our NuFace Protocol), the effects can be immediate!

Usually 3 treatments, 4 weeks apart are required to achieve optimal results. A top up every 12 months is recommended to continue to enjoy the effects.

Yes, polynucleotides are considered very safe for facial aesthetic treatments. They are biocompatible molecules naturally found in the body and are carefully purified for cosmetic use. Clinical studies have shown they are well-tolerated, with minimal risk of allergic reactions or side effects. As with any injectable treatment, it’s important to have them administered by a qualified professional to ensure the highest safety standards.

Unlike dermal fillers that simply plump the skin temporarily, polynucleotides regenerate skin at the cellular level. They boost hydration, collagen production, and skin elasticity.

Dr Khanna's NuFace Protocol combines polynucleotides with biofillers (an advanced dermal filler designed for improving skin quality alongside volume restoration).

While both treatments fall under the category of biostimulators, their ingredients, mechanisms, and use cases are significantly different.

  • Polynucleotides are new generation cellular repair stimulators, ideal for deeper concerns and sensitive areas.
  • Mesotherapy Biostimulators are vitamin-rich skin boosters, perfect for hydration, prevention, and surface-level radiance.

Each offers a unique therapeutic approach, and the choice between them depends on your individual skin condition, age, and treatment goals. In many cases, they can be combined in a personalised protocol for enhanced results. The best option for you will be discussed with your practitioner.

Prof Khanna’s unique NuFace Protocol incorporates both biofillers and polynucleotides into the same treatment. It offers unparalleled results, both to replace volume loss and provide exceptional skin rejuvenation. The NuFace Protocol is ideal for the more severe cases of volume loss.

We use the latest biofillers from Pluryal®. Regular fillers are typically used to restore the volumes of the skin by filling its depressions; Biofillers, on the other hand, act way beyond regular fillers. Whilst they increase volume similar to normal dermal fillers, Biofillers also act as biostimulators, carefully healing the skin and boosting the production of new cell layers, ensuring maximum hydration at every cellular level and increasing skin’s smoothness, elasticity, and firmness.

More-natural looking results and migration prevention

Pluryal® Biofillers are manufactured using using 3 different types of hyaluronic acid, whose particles are much smaller than those used in standard products. This promotes the penetration and distribution of the dermal filler in the tissues, preventing migration and promoting more natural-looking results.

At DrBK, we offer optional numbing cream before the treatment for those that are sensitive to needles. However most patients, particularly those who are used to 'botox', fillers or microneedling, may feel they do not require numbing at all.

We offer polynucleotide and NuFace treatments at both of our locations in Reading (Queens Road) and London (Harley St). Book now.

 

Testimonials

"I spent years not being able to smile as I hated my teeth, I was told many years ago that it would be impossible to straighten them, this left me with no confidence. Then I was told to visit Dr Bob Khanna. Today I feel great about myself, I have learned to smile again & I owe this to Dr Bob & his wonderful team. Many many thanks Dr Khanna for the work you have done, I will remain a loyal customer to you in the future." - Annie

"I could not be happier with the results Prof Bob Khanna has given me, from the very start the staff at Dr BK clinic were very informative and helpful. My nose now looks as it did before I damaged it, Prof Bob Khanna listened to my exact needs and as to what I wanted to achieve, and this shows in the way my nose now looks, I will definitely continue to come back to the clinic for future treatment." - Jason

"If you want a comprehensive, safe, quick and satisfactory treatment for your face just visit dr bob Khanna. I got my tear troughs, cheeks & non-surgical facelift done yesterday, it was pain free, took less than 20 minutes, huge transformation in a very natural way immediately and now I can't be happier. Would never get safer hands than Dr Bob's. He is a magician, love you for making me love my mirror again" - Rand

"I had been diagnosed with bruxism by my dentist and had been wearing a plastic mouthpiece every night for over five years. I read about the BK Clinic in a national newspaper and made an appointment. The team were very warm, friendly and put me at ease. Professor Khanna diagnosed my problem within minutes. Within 2 weeks I was pain-free, sleeping better and my ugly mouthpiece was ditched. I would not hesitate in recommending the DrBK Clinic, Professor Khanna is extremely knowledgeable and passionate about what he does and I only wish I had discovered his services sooner." - Sarah

"Your laser hair removal is the best treatment ever, it has been so effective and I never have to worry again about waxing, I was so grateful to find it was also not painful compared to other laser treatments I have had in the past. It felt like a warm massage. Thank you." - Cassie

Professor Bob And his wonderful caring team is the only clinic to go. I am always reassured and always feel welcome. I feel I am in the magic hands of Professor Bob. Pain free fabulous results. He simply loves his profession loves people and cares. What more an you ask for. Professor Bob achieves his work of art." - Renee

"I couldn't fault my experience, Prof Bob Khanna and the staff at the clinic were friendly and professional at all times. I would recommend visiting the clinic as you will be in the best hands. 10/10 for service and results." - Natasha

"Fantastic place, well looked after from the moment you walk through the door. I could not be any happier with my results there are amazing, wouldn't recommend anywhere else." - Jemma

care quality commission drbk reading customer service award what clinic drbk reading professional standards accredited drbk reading save face accredited clinic drbk reading customer service award what clinic drbk reading gdc qccp tatler